Here is an instruction sheet from Betterbee on the Pierco Drone Frames:http://www.betterbee.com/resources/PiercoDrone.html
I just started this year, but here is the way I am using them:
I am using 2 standard 10 frame deeps for the brood area for each hive. I have 2 drone frames per hives. One is always in the hive, usually about the 3rd frame from one side in the top deep. (I figured that they should go just inside the last frame that is completely honey/pollen.) So far I have been putting them in the upper deep just for ease of checking them.
When I inspect, typically about every 10 days or so, if the drone frame has a significant number of capped cells I swap it out with the other one. The one that is not in the hive is put in the freezer after I steal, er, um, sample
, a bit of honey from the top of the frame. Last time I got to see a drone chew his way out while I was letting the honey drip into a baking sheet... Great homeschooling stuff.
I move them from the freezer to the fridge the night before I inspect so they are not so cold when I put them back in the hive.
Since I am using one frame hive, I guess I am running only about 5% (1/20) rather than 10%. Actually now that I think about it, once you account for the honey frames in the brood boxes, one drone frame is more like 1/12. In both of my hives the bees filled the drone frames with nectar right after they drew them out for the first time, but on the next inspection they were mostly larva and capped brood. Depending on your brood nest you may be better off in the 4th position.