I grow quite a few heirloom tomatoes. I haven't had a problem with disease.
What tomato disease are you trying to get resistance to?
Is it worth the price of the Maxifort F1 seeds and silicone grafting clips?
Maxifort F1 are not heirloom tomatoes. F1 indicates they are hybrids.
I need a few hundred pounds of "Mators" this year and was wondering if that is the way to go?
Unless you are growing cherry or grape tomatoes, a few hundred pounds will not require very many plants. 20-30 pounds of tomatoes per plant is pretty common in my garden.
If I was worried about disease, I would just plant tomatoes in 5 gallon buckets with sterile soil. It's easy to propagate tomatoes as cuttings root down easily if you need more plants and only have a few seeds.