a pocket hole is nothing more than drilling a hole from the inside of the board. I was a cabinet builder/assembler for a time and that was one of the primary methods of assembling cabinet boxes with.Wikipedia-pocket hole joinery
You can use either a drill/press and a jig to create a "pocket hole" or you can use a hand held drill and first bore perpendicular to the board, turning the bit to drill parallel once it's about halfway in.
If you want to use screw heads that have sloped heads, there is an adapter that can be installed on the drill bit to make the entrance to the hole fit the screw head perfectly.
The pocket hole is used primarily with butt joints. One thing it has going for it is that there is no externally exposed wood from drilling from the outside of the box. On the con side, it's another hiding place for shb unless you fill the hole over the screw head with a cap or wood putty of some kind.