I've only been involved in tree cutouts, not bedrooms, and I've never even thought about using a bee vac. But if I did..I would probably try to vac up a couple of bees and see if they survive, before vaccing a whole colony. Usually we have scooped, brushed or tipped the majority of bees into a super, and if the rest of the bees go into the super, then we are sure we have the queen. I suppose if you were quick and bees hadn't moved out of the combs, you could try and put the brood combs in the super, and there would be a fair chance of getting the queen. We stay until dark, take the super home, then sort out the frames the next day. But with trees, you don't have the difficulty of dark recesses, working above your head, and live electric wires.
My advice would be to clean the house with the bee vac and if your girlfriend thinks it's spotless, then you probably have the suction up too high.
Well, I'm looking forward to your next tale with the swarm.