Personally, I would say it all depends on your total needs. If you are more the 'typical' home user, looking for multimedia and web stuff, I would suggest that the better "out of the box" solutions to look at would be Linux Mint and PClinuxOS.
These come with the most common drivers and codecs and formats used in multimedia and on the web included without having to search through extra repositories for them.
If you don't mind 'tinkering' then using Opensuse 11.2 or even ubuntu might be a good selection (my own personal preference being opensuse) . You will need to add a couple repositories to find those "extras" in terms of multi-meda and web codecs, formats, etc.. but it's not a deal breaker in either situation.
There are multiple versions of each distro, mostly accounting for the type of Desktop Environment you prefer. Those Desktop Environments being KDE, Gnome or Xfce. (the others that are out there are considered "window managers" and not quite full blown DE's)
To put it succinctly, Perhaps the most "Windows" like would be the KDE desktop, which is the 'default' desktop of PCLinuxOS and all the others offer a remaster of their distro using it (except for OpenSuse 11.2 which has now adopted KDE 4.4 as it's 'default' but the others are very easy to find or add.
Gnome is typically most associated with the "apple' type of presentation, having two panel bars, one at the top of the window and one at the bottom. Having said that, many Gnome based presentations now offer Gnome setup as a one bar at the bottom view.