If this queen is in a hive, you can bring her and the workers inside in a closed up nuc box. As MB said, they won't be able to get going again without more bees. But if she makes it to spring by some chance, you could give her a couple frames of bees and brood.
However you have to question why she is down to 10-12 workers. Was there a disease of some kind? Did you find dead bees? If not this could be a case of CCD and you may not want to save them (except for research). Maybe she has bad genetics, etc.