It is normal.
Last year was my first time with apiguard, and I put it on when it was very warm, 80-90F. They tore out gobs and gobs of capped brood in the first couple of days, far more than 4-10. I really freaked out, but they seemed to do OK and they all made it through the winter great.
This year the temps weren't near so high, and I didn't see anywhere near as much of that as last year. A little here and there but nothing to cause alarm. I treat beginning at the start of Sept, and this year was much cooler. And september is early enough so that they can at least get another brood cycle in before winter.
I think the temperature range should be at least in the 60s for it to be effective.