I think it depends on the level of distruction maybe? I've damaged queen cells before (were hit when pulling another frame out).
But last week I put a cage around a queen cell to protect it from neighboring bees that I was going to shake out. This cell and one very close to it were in the center of the frame just above a hole in the comb. Anyhow, the bottom of a queen cell on the other side of the frame was ajoining some of the comb below. During my manipulation the bottom of the queen cell cracked ever so slightly and became detached from the comb below. One week later, the cell looked to have been repaired a day later it looked as though the queen had emerged (hinged circular opening at the bottom the cell).